{"id":397,"date":"2022-07-19T04:30:24","date_gmt":"2022-07-19T04:30:24","guid":{"rendered":"https:\/\/planbfertility.com\/?page_id=397"},"modified":"2025-07-31T13:15:59","modified_gmt":"2025-07-31T13:15:59","slug":"pgt-pre-implantation-genetic-testing","status":"publish","type":"page","link":"https:\/\/planbfertility.com\/?page_id=397","title":{"rendered":"PGT (Pre-Implantation Genetic Testing)"},"content":{"rendered":"\t\t
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PGT
(Pre-Implantation Genetic Testing)<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Preimplantation Genetic Testing (PGT) in Hyderabad<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Plan B Fertility, located in Kondapur, offers <\/span>Preimplantation Genetic Testing (PGT) in Hyderabad<\/span>. But, what is PGT? <\/span><\/p>

PGT comprises a wide range of molecular techniques that are utilized during assisted reproduction and <\/span>in-vitro fertilization (IVF) treatment<\/span><\/a> for a range of indications prior to implantation.<\/span><\/p>

PGT, coupled with expanded carrier screening and increased parental genomic testing, has become an important technology to detect embryos at risk for genetic diseases and chromosomal abnormalities.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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To differentiate the specific types of embryo testing, PGT is divided into three subtypes, defined as:<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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1.PGT-A or Preimplantation genetic testing for Aneuploidies \u2013 previously termed as PGS.<\/p>

2.PGT-M or Preimplantation genetic testing for Monogenic\/Single gene disorders – previously termed as PGD.<\/p>

3.PGT-SR or Preimplantation genetic testing for chromosome Structural Rearrangements.<\/p>

PGT (Pre-genetic testing involves the removal) biopsy and testing of a few cells from the outer layer of the embryos created through the IVF process.<\/p>

By genetic testing, we can identify the embryos that are healthy and most likely to implant in the uterus, and result in a healthy ongoing pregnancy.<\/p>

Our Kondapur clinic offers <\/span>Preimplantation Genetic Testing (PGT) in Hyderabad<\/span> to provide patients insight into why they have had difficulty becoming or staying pregnant.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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What are the steps of the PGT process?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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  1. Consultation with our <\/span>Fertility specialist<\/span><\/a>.<\/span><\/li>
  2. Fertility testing of both partners.<\/li>
  3. Genetic testing of both partners (if not already done).<\/li>
  4. In-Vitro Fertilization (IVF) – Embryos are created and grown to the Blastocyst stage (day 5 or 6).<\/li>
  5. Blastocyst Trophectoderm (outer layer) biopsy of a few cells of each embryo.<\/li>
  6. Embryos are frozen\/cryopreserved until test results are available.<\/li>
  7. Cells removed from the embryos are sent for genetic testing (PGT-A or PGT-M or PGT-SR according to the indication).<\/li>
  8. Result usually arrives in 14 days.<\/li>
  9. Transfer embryos to the uterus of the patient in a subsequent <\/span>frozen embryo transfer (FET) cycle<\/span><\/a>.<\/span><\/li>
  10. Normal extra embryos if any remain frozen for future use.<\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    Is the embryo biopsy safe?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    In embryos that have developed to day 5 or 6 (blastocyst stage), we can see the difference between the inner cell mass (cells that will make the baby) and the trophectoderm (cells that will make the placenta).<\/p>

    We are able to safely remove cells from the future placenta without disrupting the baby-making cells.<\/p>

    The experience and expertise of the embryologists is very important in minimizing risks to the embryos.<\/p>

    The Embryologist at Plan B Fertility who does the PGT biopsy is one of the <\/span>best Embryologists in Hyderabad,<\/span> and <\/span>is highly skilled and experienced in this procedure.<\/span><\/p>

    We also believe the long-term risks of blastocyst biopsy to the embryo, pregnancy, and baby to be acceptably low as per studies conducted so far.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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    Does PGT replace prenatal testing?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    Not necessarily. While transferring an embryo that has tested \u201cnormal\u201d by PGT is expected to significantly reduce the chance for the future baby\/child to develop the genetic disorder in question, it does not entirely eliminate the risk.\u00a0<\/p>

    A Non-Invasive Prenatal Test (NIPT) or Invasive, diagnostic prenatal tests such as chorionic villus sampling (CVS) and amniocentesis are recommended for those who wish to confirm PGT results in the ongoing pregnancy or for those who have an abnormal NT scan result between 11 to 13 weeks of pregnancy.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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    Types of PGT<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    \n\t\t\t\t\t\t\t\t\t\t\t\tPGT-A <\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t

    PGT-A stands for Pre-Genetic Testing for Aneuploidies.<\/strong><\/p>

    In PGT-A, an embryo\u2019s Karyotype is tested for the presence of aneuploidies (missing or additional part or an entire chromosome), which is the leading cause for implantation failure and increased miscarriage rate in women specially in those older than 35 years.<\/span><\/p>

    The goal of PGT-A is to identify chromosomally-abnormal embryos and exclude them from transfer into the uterus. By transferring only chromosomally-normal ones, the impact of aneuploidies upon implantation failure and miscarriage can be excluded and the outcomes of IVF treatments\/chances of a successful pregnancy can be significantly improved.<\/span><\/p>

    PGT-A involves removal and testing of cells from embryos created through the IVF process. By determining how many chromosomes are present in these cells, we can identify the embryos that are most likely to implant in the uterus and result in a healthy ongoing pregnancy.<\/span><\/p>

    What will I learn about my embryos through PGT-A?<\/strong><\/p>

    PGT-A counts the number of chromosomes in each embryo\u2019s biopsied cells. Chromosomes are packages of genes, or DNA, within the cells. Humans normally have 46 chromosomes in each cell; 23 come from the sperm cell and 23 from the egg cell. Embryos with the normal number of chromosomes are considered \u201cEuploid\u201d, and those with an abnormal number of chromosomes are considered \u201cAneuploid\u201d. Aneuploidy is common in embryos, and can cause failed implantation, miscarriage, or the birth of a child with health problems.<\/span><\/p>

    For who is PGT-A recommended?<\/b><\/p>

    We offer <\/span>PGT-A testing in Hyderabad to<\/span> couples at increased risk of producing embryos with chromosomal abnormalities, and can also be employed where no familial history of a genetic condition is present.<\/span><\/p>

    Indications for PGT-A include:<\/span><\/p>