The processing of semen and selection of good quality sperms are crucial for optimal results in any ART (Assisted-Reproduction Technique) treatment. As the presence of poor quality sperms, abnormal sperms and sperms with a high DNA fragmentation can adversely affect the quality of semen, the sorting of sperm is crucial.
The conventional sperm processing and separation methods like Simple Wash and Density Gradient Centrifugation methods, only separate the sperms with high motility and do not segregate sperms with unfragmented DNA.
Microfluidics is a passive sperm segregation technique used in the ART (Assisted-Reproduction Technique) lab which helps in isolating sperm with high motility, enhanced percentage of normal morphology and significantly reduced percentage of sperm with DNA damage in comparison to the conventional methods.
The good quality motile sperms separated using Microfluidics can then be used for any ART (Assisted-Reproduction Technology) treatment like IUI/IVF/ICSI for better results.
When is Microfluidics recommended?
This technique is recommended for:
- Patients who have a high level of DFI (DNA Fragmentation Index) in their sperm sample.
- Patients who have had a history of at least one IVF/ICSI cycle and have had a poor fertilisation rate, and poor embryo quality despite a good/average oocyte quality.
- Patients who have had repeated pregnancy loss with an unidentified cause despite all the tests.